A Palladium-Catalyzed Synthesis of 4-Aryl-2-oxo-2,5-dihydrofurans [4-Aryl-2(5H)-furanones]

Abstract
Palladium-catalyzed arylation of methyl (E)-4-(2-tetrahydropyranyloxy)-2-butenoate with aryl iodides and intramolecular cyclocondensation of the resultant 3-aryl derivatives affords 4-aryl-2-oxo-2,5-dihydrofurans in moderate to good yields.

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