Synthesis of the C20−C26 Building Block of Halichondrins via a Regiospecific and Stereoselective SN2‘ Reaction
- 9 November 2002
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 4 (25) , 4427-4429
- https://doi.org/10.1021/ol026982p
Abstract
A regiospecific and stereoselective SN2‘ reaction to convert the trisylate into the vinyl iodide is presented. The homoallylic alcohol is used to direct the delivery of LiCu(Me)2.Keywords
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