Identification of nociceptin in human cerebrospinal fluid: comparison of levels in pain and non-pain states
- 1 October 1998
- journal article
- Published by Wolters Kluwer Health in Pain
- Vol. 78 (1) , 71-73
- https://doi.org/10.1016/s0304-3959(98)00130-4
Abstract
D spinal epidural anaesthesia for pain relief (Group L). Nociceptin was identified in all CSF samples with mean±SD concentrations of 52.49±34.25 and 63.39±33.26 pg/ml in groups E and L, respectively. Nociceptin was identified in 16/20 plasma samples with mean±SD concentrations of 7.59±21.58 and 13 73±23.79 pg/ml in groups E and L, respectively. CSF concentrations were significantly higher than plasma concentrations and there were no differences between groups E and L. These data report the first measurements of CSF nociceptin in man and show no association with the acute pain of labour....Keywords
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