Candida Infections in Surgical Patients

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Abstract
Serious candida infections were seen in 55 surgical patients from Jan., 1977-Dec., 1980. Most of the patients had compromising underlying conditions and many were elderly. Broad-spectrum antibiotics and total parenteral nutrition (TPN) appeared to predispose patients to candida infections. Mortality rate from candida was 38%. A high percentage of patients with positive blood or bile cultures died as a result of candida infection. Therapy with i.v. amphotericin B was highly effective if given in adequate dosage. No patient receiving > 200 mg of amphotericin B died, but the mortality rate was 56% in those receiving lower doses.