Abstract
Summary Iso-antibody production in the rabbit is greatly enhanced by pretreatment of the recipients with an intradermal injection of BCG. Of 46 animals given the BCG pretreatment 26 produced isohemagglutinin when stimulated with donor red blood cells, whereas only 3 out of 27 produced isohemagglutinin when the BCG pretreatment was omitted. Antisera to 7 different antigens in the rabbit have been prepared by the use of BCG pretreatment.

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