Ethylene Glycol Poisoning. The Value of Glycolic Acid Determinations for Diagnosis and Treatment
- 1 January 1986
- journal article
- research article
- Published by Taylor & Francis in Journal of Toxicology: Clinical Toxicology
- Vol. 24 (5) , 389-402
- https://doi.org/10.3109/15563658608992602
Abstract
Glycolic acid is the ethylene glycol (EG) metabolite that accumulates in the highest concentrations in the blood and may be the major contributing factor to the acute toxicity of EG. Serum and urine levels of glycolic acid have been found to correlate directly with clinical symptoms and mortality in poisoning cases, making it a valuable diagnostic tool. A high pressure liquid chromatographic (HPLC) method for quantitation of glycolic acid in serum was used in several cases of EG ingestion presented to the Louisiana Regional Poison Control Center. The data collected in this study support the value of glycolic acid determination for diagnosis and evaluation of patients poisoned by EG.This publication has 14 references indexed in Scilit:
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