Synthesis and nicotinic acetylcholine receptor binding affinities of 2- and 3-isoxazolyl-8-azabicyclo[3.2.1]octanes
- 30 April 2004
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 14 (7) , 1775-1778
- https://doi.org/10.1016/j.bmcl.2004.01.025
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- The antinociceptive effects of α7 nicotinic agonists in an acute pain modelNeuropharmacology, 2000
- Nociceptive and antinociceptive responses to intrathecally administered nicotinic agonistsNeuropharmacology, 1998
- Neuronal Nicotinic Acetylcholine Receptors as Targets for Drug DiscoveryJournal of Medicinal Chemistry, 1997
- Fluoro-norchloroepibatidine: Preclinical assessment of acute toxicityNuclear Medicine and Biology, 1997
- Synthesis of optically pure epibatidine analogs: (1R, 2R, 5S)-2β-(2-chloro-5-pyridinyl)-8-azabicyclo[3.2.1]octane and (1R, 2S, 5S)-2α-(2-chloro-5-pyridinyl)-8-azabicyclo[3.2.1]octane from (−)-cocaineTetrahedron Letters, 1997
- Synthesis and nicotinic activity of epiboxidine: an isoxazole analogue of epibatidineEuropean Journal of Pharmacology, 1997
- Evaluation of anti-nociceptive effects of neuronal nicotinic acetylcholine receptor (NAChR) ligands in the rat tail-flick assayNeuropharmacology, 1996
- Epibatidine: Pharmacological Properties of a Novel Nicotinic Acetylcholine Receptor Agonist and Analgesic AgentCNS Drug Reviews, 1996
- Epibatidine is a nicotinic analgesicEuropean Journal of Pharmacology, 1993
- Epibatidine: a novel (chloropyridyl)azabicycloheptane with potent analgesic activity from an Ecuadoran poison frogJournal of the American Chemical Society, 1992