Smoking and Pulmonary Surfactant

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Abstract
Elsewhere in this issue of the Journal Finley and Ladman report further intriguing observations on the material obtained by regional lavage from the lungs of healthy young cigarette smokers and nonsmokers. To their previous demonstration1 that in smokers the yield of free particulate matter was much smaller and that of macrophages was much larger than in nonsmokers, they now add the results of analysis of free and cell-bound lipids. They found no qualitative differences in phospholipid and neutral lipid species either free or cell-bound, but they demonstrated that in smokers, as compared to nonsmokers, the amount of phosphatidylcholine (PC) harvested . . .