The effect of Bay K 8644 on contraction mediated by α‐adrenoceptors in the rat saphenous vein

Open Access

1 June 1985

journal article
Published by Wiley in British Journal of Pharmacology

Vol. 85 (2) , 317-319
https://doi.org/10.1111/j.1476-5381.1985.tb08862.x

Abstract

The effect of Bay K 8644 on the contractile responses of the rat saphenous vein to KC1, noradrenaline, methoxamine, and B-HT 920 were studied. In all cases, Bay K 8644 potentiated the responses. These results confirmed the suggestion that α-adrenoceptor agonists initiated contraction in the rat saphenous vein by opening the potential-operated calcium channels.

Keywords

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