Chloramphenicol concentrations in calf muscle tissue

Abstract
SUMMARY: Twenty-five 9- to 11-week-old calves were administered 2 doses of chloramphenicol prepared in propylene glycol (13.6 mg/kg of body weight iv; 6.8 mg/kg im; or 13.6 mg/kg im) at 24-hour intervals. Calves were euthanatized at designated times from 2 to 72 hours after the last dose was administered. Muscle tissues were collected immediately after euthanasia, and chloramphenicol concentrations in the tissues were determined.

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