In vitro metabolism of deoxycoformycin in human T lymphoblastoid cells. Phosphorylation of deoxycoformycin and incorporation into cellular DNA.
Open Access
- 1 August 1984
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 259 (15) , 9426-9433
- https://doi.org/10.1016/s0021-9258(17)42718-9
Abstract
No abstract availableThis publication has 19 references indexed in Scilit:
- Conversion of a stem cell leukemia from a T-lymphoid to a myeloid phenotype induced by the adenosine deaminase inhibitor 2'-deoxycoformycin.Proceedings of the National Academy of Sciences, 1984
- Phenotypic conversion of acute leukaemia from T‐lymphoblastic to myeloblastic induced by therapy with 2′‐deoxycoformycinBritish Journal of Haematology, 1983
- Biochemical and Functional Abnormalities in Lymphocytes from an Adenosine Deaminase-deficient Patient during Enzyme Replacement TherapyJournal of Clinical Investigation, 1981
- Adenosine deaminase and adenylate deaminase: comparative kinetic studies with transition state and ground state analog inhibitorsBiochemistry, 1980
- ATP depletion as a consequence of adenosine deaminase inhibition in man.Proceedings of the National Academy of Sciences, 1980
- Purinogenic Immunodeficiency DiseasesJournal of Clinical Investigation, 1979
- The metabolism of 2'-deoxycoformycin by L1210 cells invitroBiochemical Pharmacology, 1979
- Deoxyadenosine triphosphate as a potentially toxic metabolite in adenosine deaminase deficiency.Proceedings of the National Academy of Sciences, 1978
- ISOLATION AND PROPERTIES OF A VIDARABINE DEAMINASE INHIBITOR, CO‐VIDARABINEAnnals of the New York Academy of Sciences, 1977
- Deoxynucleotide-Polymerizing Enzymes of Calf Thymus Gland, IV. Inhibition of Terminal Deoxynucleotidyl Transferase by Metal LigandsProceedings of the National Academy of Sciences, 1970