Cystic Kidney Diseases: All Roads Lead to the Cilium
- 1 August 2004
- journal article
- review article
- Published by American Physiological Society in Physiology
- Vol. 19 (4) , 225-230
- https://doi.org/10.1152/physiol.00003.2004
Abstract
Cystic kidney disorders are one of the leading causes of end-stage renal disease. Numerous experimental animal models have been used to understand the disease pathogenesis. Recent advancements in this field have provided a surprising finding: that many of the proteins associated with cystic kidney disease localize to a nearly forgotten organelle, the primary cilium.Keywords
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