Abstract
AS EARLY as 1910 Laws1 described the So-Called "Nitroglycerin head," and several papers soon followed that helped to elucidate the physiologic effects of nitroglycerin on the human body, especially after the absorption of extremely minute quantities through the unbroken skin, or even the inhalation of the fumes when dynamite is used for blasting purposes.2 3 4 Men working in powder plants soon acquire a rather transient immunity to nitroglycerin that can rapidly be lost over a period such as a weekend or during a vacation. Return to the job consequently results in a severe headache, which is also experienced by men first . . .

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