Migration of Leishmania donovani Amastigotes in the Cerebrospinal Fluid
- 1 December 1996
- journal article
- case report
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 55 (6) , 652-654
- https://doi.org/10.4269/ajtmh.1996.55.652
Abstract
A 10-year-old boy had been suffering from kala-azar (visceral leishmaniasis) for two and a half years. He failed to respond to all known anti-leishmanial treatment regimens. Even the drastic step of splenectomy failed to cure him. In November 1991, he presented with symptoms of meningitis. A diagnostic lumbar puncture revealed leishmanial amastigotes in his cerebrospinal fluid. The patient was finally cured with a course of amphotericin B, a drug known to cross the blood-brain barrier.Keywords
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