Glucose, fructose, lactate and pyruvate in blood and lactate and pyruvate in parotid saliva in response to sugars with and without other foods

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Abstract
Blood and parotid saliva responses to glucose and fructose, to equal amounts of the sugars given together, or to sucrose when added to a breakfast containing fat and protein were compared with responses to glucose and fructose alone. Parameters measured were glucose, fructose, lactate, and pyruvate in blood and lactate and pyruvate in parotid saliva. When glucose was given alone, the response in serum was not different from that when it was given with the breakfast. When fructose was given alone, fructose response in serum was greater than when fructose was given with breakfast. There were no differences between responses of glucose or of fructose when breakfast with the mixture of glucose and fructose was compared with breakfast with sucrose. Responses in lactate and pyruvate in both blood and saliva were similar when breakfast with fructose, the mixture of glucose and fructose, or sucrose was given. Lactate/pyruvate ratios in blood were lower when the breakfast without sugar added was consumed. Lactate in blood was highly correlated with lactate in saliva after fructose alone, and after the breakfast with the mixture of glucose and fructose or sucrose. Pyruvate levels in blood were not highly correlated with those in saliva.