ADENOCARCINOMA OF PROSTATE IN PERSPECTIVE

  • 1 January 1978
    • journal article
    • review article
    • Vol. 119  (9) , 1077-+
Abstract
Adenocarcinoma of the prostate is responsible for 1 of very 9 deaths from cancer in Canada. Epidemiologic factors are considered and current staging systems are outlined. The American Urological System is recommended for staging because of its ability to reflect changes in the understanding of the biologic behavior of this neoplasm. The adoption of a quantitative grading scheme is suggested to complement the information obtained from the staging assessment. The routes of spread of this disease and the procedures used to assess metastatic involvement are described. Immunologic methods for the analysis of prostatic acid phosphatase are superior to the enzymatic methods previously used and the role of the new techniques is discussed. Radiotherapy and endocrine therapy are emphasized for the treatment of this neoplasm, and the concept of withholding endocrine therapy until symptoms appear is discussed. Potential future developments in this field are considered.