Parental Major Depression and the Risk of Depression and Other Mental Disorders in Offspring
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Open Access
- 1 April 2002
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 59 (4) , 365-374
- https://doi.org/10.1001/archpsyc.59.4.365
Abstract
AVAST NUMBER of studies have investigated the association between depression in parents and psychopathology in their offspring. Studies using the "top-down" approach have consistently shown that offspring of depressed parents have a substantially increased risk for experiencing not only depressive disorders, but also other psychopathology, such as anxiety or substance-use disorders.1-17 From another perspective, "bottom-up" studies examining clinically referred depressed children and adolescents have reported increased rates of depression and other forms of psychopathology in their adult relatives.18-25Keywords
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