Effect of Dibenzyline on Skin Temperature, Peripheral Blood Flow, and Vasomotor Responses in Normal Patients and Patients with Increased Vasoconstrictor Tone
- 1 August 1953
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 8 (2) , 224-231
- https://doi.org/10.1161/01.cir.8.2.224
Abstract
Dibenzyline is an orally effective, moderately potent, long acting, adrenergic blocking agent. The drug is capable of at least partially preventing the vasoconstrictor responses to cold and to injected Neosynephrine. Blood flow and temperature responses to this agent do not always parallel results obtained following surgical sympathectomy, but the degree of effect appears to be sufficient to produce a clinical response. Side effects and the development of "tolerance" may limit the use of Dibenzyline in clinical medicine.Keywords
This publication has 3 references indexed in Scilit:
- Clinical Applications of Adrenergic Blockade in Vascular Diseases With Special Reference To Dibenamine and 688aAngiology, 1951
- Effect of Oral 688A (N-Phenoxyisopropyl-N-Benzyl- -Chloroethylamine Hydrochloride) on Blood Pressure in Normotensive and Hypertensive Subjects.Experimental Biology and Medicine, 1951
- DIGITAL CUTANEOUS BLOOD FLOW, CARDIAC OUTPUT, BLOOD PRESSURE AND PULSE RATE IMMEDIATELY FOLLOWING THE ADMINISTRATION OF FOUR POTENTIAL VASODILATORS*The Lancet Healthy Longevity, 1951