Methotrexate in Abdominal Pregnancy
- 21 April 1969
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 208 (3) , 529-531
- https://doi.org/10.1001/jama.1969.03160030103019
Abstract
Laparotomy was performed at term on a patient with an abdominal pregnancy and she was delivered of a normal, viable infant. The placenta was not disturbed. The umbilical arteries were catheterized, and the placenta was perfused with methotrexate in an effort to shorten its life and vascularity. Urinary chorionic gonadotropin excretion was quantitated following delivery and after treatment with methotrexate. A rapid drop in the chorionic gonadotropin titer occurred. Roentgenographic contrast studies demonstrated the vascularity of the placenta before and after treatment.Keywords
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