Fatty Liver and Pleural Effusion with Ibuprofen Therapy
- 1 August 1977
- journal article
- case report
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 87 (2) , 200-201
- https://doi.org/10.7326/0003-4819-87-2-200
Abstract
New nonsteroidal anti-inflammatory agents have been notably free from serious side effects. We report here a case of fatal fatty metamorphosis of the liver and pleural effusions in an atopic individual with mixed connective tissue disease treated with ibuprofen (Motrin®) and ampicillin. A 48-year-old woman was first seen on 19 June 1975. She complained of symmetrical polyarthritis for 7 years as well as dry eyes and mouth, Raynaud's phenomenon, dysphagia, and weight loss for the last year. Only aspirin, 2.6 g daily, had been taken for the 3 months before her initial evaluation. She was allergic to streptomycin and para-aminosalicylicKeywords
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