Immunity Against Experimental Cholera

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Abstract
Choleragen, an antigenic, choleragenic protein moiety isolated from cultures of chlorea vibrios, administered parenterally, immunized adult rabbits against intestinal challenge with either living cholera vibrios or with choleragen. A degree of resistance against choleragen could be passively transferred by serum to infant rabbits. These results suggest that choleragen offers promise as an effect immunogen against cholera.