Hemochromatosis with Megaloblastic Anemia Responding to Folic Acid
- 20 March 1958
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 258 (12) , 586-589
- https://doi.org/10.1056/nejm195803202581204
Abstract
THE pattern of iron metabolism in hemochromatosis has been well established. Thus, it has been shown that the absorption of iron from the gastrointestinal tract is greatly increased in addition to the increased affinity for iron by the body tissues.1 2 3 Congenital and acquired hemochromatosis have the same fundamental defect of increased iron absorption. In the former, there appears to be an inherited defect in the so-called mucosal "block," thus allowing the absorption of undue amounts of iron from the intestinal tract. Most commonly, patients with the congenital type of hemochromatosis have normal hemoglobin levels, and thus they can afford frequent . . .Keywords
This publication has 12 references indexed in Scilit:
- THE METABOLISM OF FOLIC ACID IN CIRRHOSISAnnals of Internal Medicine, 1956
- Pyridoxine Responsive Anemia in the Human Adult.Experimental Biology and Medicine, 1956
- IDIOPATHIC HEMOCHROMATOSIS, AN IRON STORAGE DISEASEMedicine, 1955
- THE ANEMIA OF LIVER DISEASE: OBSERVATIONS ON ITS MECHANISM 1Journal of Clinical Investigation, 1955
- The Occurrence of Megaloblastic Erythropoiesis in Patients with HemochromatosisBlood, 1952
- IRON OVERLOAD (HEMOSIDEROSIS) AGGRAVATED BY BLOOD TRANSFUSIONSArchives of internal medicine (1960), 1949
- HEMOSIDEROSIS IN REFRACTORY ANEMIAArchives of internal medicine (1960), 1949
- STUDIES IN IRON TRANSPORTATION AND METABOLISMBlood, 1948
- APLASTIC ANEMIA AND ITS ASSOCIATION WITH HEMOCHROMATOSISArchives of internal medicine (1960), 1945
- AN UNUSUAL CASE OF APLASTIC ANÆMIA WITH ORGAN CHANGES RESEMBLING HÆMOCHROMATOSISThe Medical Journal of Australia, 1942