Pharmacological studies on meprobamate incorporation in human beard hair
- 1 September 1993
- journal article
- Published by Springer Nature in International journal of legal medicine
- Vol. 105 (5) , 283-287
- https://doi.org/10.1007/bf01370386
Abstract
The time course of appearance of meprobamate in beard hair after single oral administration (400, 800, or 1200mg) was monitored in 3 groups of 4 subjects by GC/MS. Meprobamate appeared in beard hair approximately 4–5 days after administration and peaked during the 7–9th day. Drug levels in beard hair appeared to be dose-related. Der zeitliche Verlauf der Ablagerung von Meprobamat in Barthaaren wurde nach einmaliger Einnahme von 400, 800, bzw. 1200mg in 3 Gruppen von je 4 Personen mittels GC/MS untersucht. Meprobamat wurde in Haar ca. 4–5 Tagen nach Einnahme nachweisbar; höchste Haarkonzentrationen wurden nach ca. 7–9 Tagen erreicht. Es wurden Korrelationen zwischen Haarkonzentration an Meprobamat und eingenommener Dosis festgestellt.Keywords
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