THE MAJOR PSYCHOSES AND NEUROSES AS OMEGA-3 ESSENTIAL FATTY-ACID DEFICIENCY SYNDROME - SUBSTRATE PELLAGRA

  • 1 January 1981
    • journal article
    • research article
    • Vol. 16  (9) , 837-850
Abstract
Pellagra was once a major cause of 3 behaviorally different mental disorders, schizophreniform, manic-depressive-like and phobic neurotic, plus drying dermatoses, autonomic neuropathies, tinnitus and fatigue. All 3 of the corresponding present-day mental diseases exhibit, statistically, the same pellagraform physical disorders but ameliorate not so much with vitamins as with supplements of a newly discovered trace omega-3 essential fatty acid (w3-EFA), which provides the substrate upon which niacin and other B vitamin holoenzymes act uniquely to form the prostaglandin 3 series tissue hormones regulating neurocircuits en block. Since present-day refining and food selection patterns, and pure corn diets, deplete both the B vitamins and w3-EFA, the existence of therapeutically cross-reacting homologous catalyst and substrate deficiency forms of pellagra are postulated, the 1st contributing to the B vitamin deficiency epidemics of 50-100 yr ago, the 2nd to the more recent endemic Diseases of Western Civilization, which express in certain genetic subgroups as the major mental illnesses of today.

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