Cost-Effectiveness of Antiseptic-Impregnated Central Venous Catheters for the Prevention of Catheter-Related Bloodstream Infection

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Abstract
Central venous catheters are essential in caring for many hospitalized patients who are critically ill and those requiring repeated venous access. Despite the advantages of their use, such as the ability to administer medications and large fluid volumes, central venous catheters are associated with mechanical and significant infectious complications.1 Catheter-related bloodstream infection (CR-BSI) occurs with 3% to 7% of catheters and affects more than 200,000 patients per year in the United States.2,3 The attributable mortality of CR-BSI ranges from approximately 10% to 25%, and CR-BSI has been associated with significant increases in the length of hospitalization and medical care costs.4-7