INFLUENCE OF 5-NITRO-2-FURYL ACRYLIC-ACID ON HUMAN-FIBROBLASTS CULTIVATED INVITRO

  • 1 January 1979
    • journal article
    • research article
    • Vol. 26  (3) , 267-274
Abstract
The in vitro effects of 5-nitro-2-furyl acrylic acid [a potenital carcinogen] or growth activity of EUE human fibroblasts were studied. The course and intensity of macromolecular syntheses, mainly DNA synthesis in these cells were noted. The cytotoxic effects of 5-nitro-2-furyl acrylic acid are apparently also connected with its genotoxic effects, since that substance will induce damage to DNA in human cells.

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