Glutathione decreases in dopaminergic PC12 cells interfere with the ubiquitin protein degradation pathway: relevance for Parkinson's disease?
Open Access
- 1 February 2002
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 80 (4) , 555-561
- https://doi.org/10.1046/j.0022-3042.2001.00009.x
Abstract
Parkinson's disease (PD) is characterized by the presence of proteinaceous neuronal inclusions called Lewy bodies in susceptible dopaminergic midbrain neurons. Inhibition of the ubiquitin-proteasome ...Keywords
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