CHROMOSIN, A DESOXYRIBOSE NUCLEOPROTEIN COMPLEX OF THE CELL NUCLEUS
Open Access
- 20 November 1946
- journal article
- Published by Rockefeller University Press in The Journal of general physiology
- Vol. 30 (2) , 117-148
- https://doi.org/10.1085/jgp.30.2.117
Abstract
A desoxyribose nucleoprotein complex, which we have referred to as a chromosin, has been prepared from a great variety of cells, mainly animal but also plant and bacterial. A chromosin is derived from the cell nucleus. In the course of preparation precautions have been taken to prevent contamination by cytoplasmic constituents. To assure the nuclear origin of all components of chromosin, nuclei have in several instances been isolated before extraction was begun. Because of the precautions taken, chromosins do not contain detectable quantities of ribose nucleoproteins; but, incidentally, extraction of ribose nucleoproteins, free of desoxyribose compounds, has also been described in this paper.Keywords
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