A Single Enzyme Catalyses Formation of Trypanothione from Glutathione and Spermidine in Trypanosoma cruzi
Open Access
- 1 September 2002
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (39) , 35853-35861
- https://doi.org/10.1074/jbc.m204403200
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Roles of the Glutathione- and Thioredoxin-Dependent Reduction Systems in the Escherichia Coli and Saccharomyces Cerevisiae Responses to Oxidative StressAnnual Review of Microbiology, 2000
- Glutathione and trypanothione in parasitic hydroperoxide metabolismFree Radical Biology & Medicine, 1999
- Down-regulation of Leishmania donovani trypanothione reductase by heterologous expression of a trans-dominant mutant homologue: Effect on parasite intracellular survivalProceedings of the National Academy of Sciences, 1998
- Disruption of the trypanothione reductase gene of Leishmania decreases its ability to survive oxidative stress in macrophagesThe EMBO Journal, 1997
- Polyamines as Targets for Therapeutic InterventionAnnual Review of Pharmacology and Toxicology, 1995
- METABOLISM AND FUNCTIONS OF TRYPANOTHIONE IN THE KINETOPLASTIDAAnnual Review of Microbiology, 1992
- Trypanothione: A Novel Bis(glutathionyl)spermidine Cofactor for Glutathione Reductase in TrypanosomatidsScience, 1985
- Identification of a novel, thiol-containing co-factor essential for glutathione reductase enzyme activity in trypanosomatidsMolecular and Biochemical Parasitology, 1985
- POLYAMINESAnnual Review of Biochemistry, 1984
- GLUTATHIONEAnnual Review of Biochemistry, 1983