A View of Genetics

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Abstract
The experimental control of cellular genotype is one of the measures of the scope of genetic science. However, nucleic genes will not be readily approached for experimental manipulation except by reagents that mimic them in periodic structure. Specifically induced mutation, if ever accomplished, will then consist of an act of genetic recombination between the target desoxynucleic acid and the controlled information specified by the reagent. Methods for the step-wise analysis and re-assembly of nucleic acids are likely to be perfected in the near future in pace with the accessibility of nucleic acid preparations which are homogenous enough to make their use worth while. For the immediate future, it is likely that the greatest success will attend the use of biological reagents to furnish the selectivity needed to discriminate one among innumerable classes of polynucleotides. Synthetic chemistry is, however, challenged to produce model polymers that can emulate the essential features of genetic systems.
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