The mammalian metabolite, 2-methoxyestradiol, affects p53 levels and apoptosis induction in transformed cells but not in normal cells

This publication has 22 references indexed in Scilit:

• A Movable and Regulable Inactivation Function within the Central Region of a Temperature-sensitive p53 Mutant
  Journal of Biological Chemistry, 1995
• Synthesis, Antitubulin and Antimitotic Activity, and Cytotoxicity of Analogs of 2-Methoxyestradiol, an Endogenous Mammalian Metabolite of Estradiol That Inhibits Tubulin Polymerization by Binding to the Colchicine Binding Site
  Journal of Medicinal Chemistry, 1995
• Involvement of p53 Expression in cAMP-Mediated Apoptosis in Immortalized Granulosa Cells
  Experimental Cell Research, 1995
• Absence of Radiation-induced G1 Arrest in Two Closely Related Human Lymphoblast Cell Lines That Differ in p53 Status
  Published by Elsevier ,1995
• The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth
  Nature, 1994
• SV40 T antigen induced chromosomal changes reflect a process that is both clastogenic and aneuploidogenic and is ongoing throughout neoplastic progression of human fibroblasts
  Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1992
• Frequent deletions in nine newly immortal human cell lines
  Cancer Genetics and Cytogenetics, 1992
• Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53
  Cell, 1990
• SV40 T antigen alone drives karyotype instability that precedes neoplastic transformation of human diploid fibroblasts
  Journal of Cellular Biochemistry, 1990
• The cytotoxic effects of estradiol-17β, catecholestradiols and methoxyestradiols on dividing MCF-7 and Hela cells
  The Journal of Steroid Biochemistry and Molecular Biology, 1989