Biomarkers for Chronic Heart Failure
- 1 December 2009
- journal article
- review article
- Published by Springer Nature in Herz
- Vol. 34 (8) , 589-593
- https://doi.org/10.1007/s00059-009-3316-4
Abstract
Cardiac biomarkers are very important in diagnosis, risk stratification, and management of patients with heart failure. Although not meeting all criteria for an ideal biomarker, natriuretic peptides primarily have a diagnostic and prognostic role. Other routinely available and newly emerging biomarkers have a complementary role in patient management; thus multimarker strategy might be warranted in future. The quest for a single marker or a combination is ongoing and several established, widely available biomarkers might have been overlooked in the field of heart failure. The authors review some of those biomarkers and speculate on the possible roles of combining two or more of them. Kardiale Biomarker sind wichtig für Diagnostik, Risikoeinschätzung und Behandlung von herzinsuffizienten Patienten. Natriuretische Peptide haben primär eine diagnostische und prognostische Aussagekraft. Den idealen Biomarker für Herzinsuffizienz gibt es aber noch nicht. In diesem Forschungsbereich sind noch viele Studien notwendig. Routinemäßige und neu entwickelte Biomarker haben teilweise komplementäre Aussagekraft und können möglicherweise in der Zunkunft in einer Multimarkerstrategie die Behandlung herzinsuffizienter Patienten positiv steuern. In diesem Review werden sowohl einzelne Biomarker wie auch Kombinationen von Biomarkern und ihre Anwendung in der klinischen Praxis diskutiert.Keywords
This publication has 51 references indexed in Scilit:
- Effect of rosuvastatin in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trialThe Lancet, 2008
- Midregional pro-atrial natriuretic peptide is a useful indicator for the detection of impaired left ventricular function in patients with coronary artery diseaseInternational Journal of Cardiology, 2008
- ProANP and NT-proBNP levels to prospectively assess cardiac function in breast cancer patients treated with cardiotoxic chemotherapyInternational Journal of Cardiology, 2007
- Rosuvastatin in Older Patients with Systolic Heart FailureNew England Journal of Medicine, 2007
- Atrial natriuretic peptide and related peptidescclm, 2007
- Cystatin C, Left Ventricular Hypertrophy, and Diastolic Dysfunction: Data From the Heart and Soul StudyJournal of Cardiac Failure, 2006
- Role and importance of biochemical markers in clinical cardiologyEuropean Heart Journal, 2004
- Effect of anemia on exercise tolerance in chronic heart failure in menThe American Journal of Cardiology, 2003
- Molecular cloning and sequence analysis of cDNA coding for the precursor of the human cysteine proteinase inhibitor cystatin CPublished by Wiley ,2001
- Tumour Necrosis Factor in Chronic Heart FailureDrugs, 2000