The molecular genetics of human chromosome 6.
- 1 November 1987
- journal article
- review article
- Published by BMJ in Journal of Medical Genetics
- Vol. 24 (11) , 649-658
- https://doi.org/10.1136/jmg.24.11.649
Abstract
Chromosome 6 contains several clinically important markers as well as classical enzyme loci, proto-oncogenes, and a growing number of anonymous DNA restriction fragment length polymorphisms (RFLPs). It is also of unique interest because of the location of the major histocompatibility complex (MHC) on the short arm, at 6p21.3. The MHC is one of the most detailed areas of the human genetic map to date and many important diseases, some of a suspected autoimmune aetiology, are associated with it.Keywords
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