The putative «silent» 5-HT1A receptor antagonist, WAY 100635, has inverse agonist properties at cloned human 5-HT1A receptors
- 1 July 2000
- journal article
- Published by Elsevier in European Journal of Pharmacology
- Vol. 401 (1) , 9-15
- https://doi.org/10.1016/s0014-2999(00)00410-6
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- Mechanisms of Agonism and Inverse Agonism at Serotonin 5‐HT1A ReceptorsJournal of Neurochemistry, 2000
- Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a []GTPγS binding studyEuropean Journal of Pharmacology, 1998
- Agonist-independent Activation of Gz by the 5-Hydroxytryptamine1A Receptor Co-expressed in Spodoptera frugiperda CellsPublished by Elsevier ,1997
- Sodium Dependency of Constitutive Activity at 5‐HT1Dα/1D/β ReceptorsAnnals of the New York Academy of Sciences, 1997
- Characterisation of a cloned human 5-HT1A receptor cell line using [35S]GTPγS bindingEuropean Journal of Pharmacology, 1997
- Inhibition of the constitutive activity of human 5‐HT1A receptors by the inverse agonist, spiperone but not the neutral antagonist, WAY 100,635British Journal of Pharmacology, 1997
- Effects of 5-HT1A receptor antagonists on hippocampal 5-hydroxytryptamine levels: (S)-WAY100135, but not WAY100635, has partial agonist propertiesEuropean Journal of Pharmacology, 1996
- Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonistBehavioural Brain Research, 1995
- A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635European Journal of Pharmacology, 1995
- Precoupling of GiGo-linked receptors and its allosteric regulation by monovalent cationsLife Sciences, 1993