The Shwartzman Phenomenon. I. Inhibitory Action of Nitrogen Mustard (HN2)
- 1 August 1950
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 74 (4) , 749-751
- https://doi.org/10.3181/00379727-74-18036
Abstract
The inhibitory action of HN2 in the Shwartzman phenomenon is confirmed, but evidence is presented that the HN2 acts systemically rather than locally on the endo-thelium of the preparatory site, since protection of the preparatory site from the action of the HN2 by means of a skin clamp, fails to influence the inhibition, while occlusion of the aorta with protection of the lower limbs decreases or prevents the inhibitory action.Keywords
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