Cytogenetic studies on 19 papillary thyroid carcinomas
- 1 October 1992
- journal article
- research article
- Published by Wiley in Genes, Chromosomes and Cancer
- Vol. 5 (3) , 206-211
- https://doi.org/10.1002/gcc.2870050306
Abstract
Short-term cultures from 19 papillary thyroid adenocarcinomas revealed clonal numerical and/or structural chromosomal changes in 13 tumors, nonclonal abnormalities in one tumor, and only normal karyotypes in five tumors. Clonal abnormalities of chromosome 10 were present in three tumors, two of which had the translocation t(7; 10)(q35;q21). Numerical abnormalities of chromosome 17 were detected in two tumors.Keywords
This publication has 26 references indexed in Scilit:
- Deletion of part of the long arm of chromosome 13 as the only karyotypic aberration in a follicular thyroid adenomaCancer Genetics and Cytogenetics, 1991
- Cytogenetics of six follicular thyroid adenomas including a case report of an oxyphil variant with t(8;14)(q13;q24.1)Cancer Genetics and Cytogenetics, 1991
- Cytogenetic analysis of a multinodular thyroid goiterCancer Genetics and Cytogenetics, 1991
- Cytogenetic abnormalities in thyroid adenomasCancer Genetics and Cytogenetics, 1991
- PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomasPublished by Elsevier ,1990
- A translocation (7;10)(q35;q21) in a differentiated papillary carcinoma of the thyroidCancer Genetics and Cytogenetics, 1989
- Chromosome studies in thyroid neoplasiaCancer, 1989
- Cytogenetic findings on eight follicular thyroid adenomas including one with a t(10;19)Cancer Genetics and Cytogenetics, 1989
- Molecular Cloning of PTC, a New Oncogene Found Activated in Human Thyroid Papillary Carcinomas and Their Lymph Node MetastasesAnnals of the New York Academy of Sciences, 1988
- A new oncogene in human thyroid papillary carcinomas and their lymph-nodal metastasesNature, 1987