Restriction mapping of a new deletion responsible forGγ(δβ)° thalassaemia
- 1 January 1981
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 9 (24) , 6813-6825
- https://doi.org/10.1093/nar/9.24.6813
Abstract
DNA from individuals heterozygous for (G)gamma(deltabeta)(o) thalassaemia has been studied by restriction endonuclease analysis. The results reveal a new molecular defect associated with this condition. A total of three defects is now responsible for the one single phenotype, thereby emphasising the complex relationship between genotype and phenotype among the disorders of beta-like globin synthesis in man.Keywords
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