INTRA-OCULAR AND INTRACRANIAL PRESSURE

Abstract
The results of simultaneous investigation of analogous biologic processes may have significance reaching beyond an understanding of individual organs, for such study touches directly on the unity of the organism. The many analogies between the eyeball and the cranium have been emphasized by Thomson Henderson1in 1910 and by Wegefarth and Weed2in 1914, but Mestrezat,3in 1912, established the fundamental identity of aqueous humor and cerebrospinal fluid. These relationships have been discussed recently by one of us (F. F.-S.4) in a critical review on the nature of the cerebrospinal fluid. The evidence indicates that this fluid, and also the aqueous humor, both of which are nearly protein-free, are dialysates in equilibrium with the blood plasma. This concept, first formulated by Mestrezat,3follows in the main the ideas on fluid exchange between capillaries and tissue spaces set forth by Starling5in 1909; it assumes

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