Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis
Open Access
- 23 July 2003
- journal article
- website
- Published by Wiley in Aging Cell
- Vol. 2 (4) , 209-217
- https://doi.org/10.1046/j.1474-9728.2003.00054.x
Abstract
RNA interference (RNAi) can achieve sequence‐selective inactivation of gene expression in a wide variety of eukaryotes by introducing double‐stranded RNA corresponding to the target gene. Here we exp...Keywords
This publication has 42 references indexed in Scilit:
- Stable suppression of tumorigenicity by virus-mediated RNA interferenceCancer Cell, 2002
- RNAi in Human CellsMolecular Cell, 2002
- A System for Stable Expression of Short Interfering RNAs in Mammalian CellsScience, 2002
- Retrovirus-delivered siRNABMC Biotechnology, 2002
- Short 5′-phosphorylated double-stranded RNAs induce RNA interference in DrosophilaCurrent Biology, 2001
- From charcot to lou gehrig: deciphering selective motor neuron death in alsNature Reviews Neuroscience, 2001
- In vitro photochemical cataract in mice lacking copper-zinc superoxide dismutaseFree Radical Biology & Medicine, 2001
- Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systemsProceedings of the National Academy of Sciences, 2001
- Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cellsNature, 2001
- RNA interference is mediated by 21- and 22-nucleotide RNAsGenes & Development, 2001