Pharmacological properties, cholinesterase activity and anatomy of nerve—muscle junctions in vagus‐innervated frog sartorius

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Abstract
1. The pharmacological properties of the nerve—muscle junctions of vagus-innervated frog sartorius muscles were investigated. Vagus-evoked junctional potentials were ten times more sensitive to hexamethonium than were control end-plate potentials from muscles re-innervated with sartorius nerve. Hexamethonium did not affect passive electrical muscle membrane properties or quantal content. The sensitivity of vagus junctions to D-tubocurarine (dTC) did not differ from the controls.