Acoustic measurement of erythrocyte compressibility

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Abstract
Adiabatic compressibility of red blood cells obtained from humans by a modified ultrasound velocity technique was determined and correlated to the mean cellular Hb concentration [MCHC] of the red blood cells. The ultrasound technique has an accuracy of better than 0.1%. The results show a mean adiabatic compressibility of 34.814 .times. 10-12 .+-. 0.861 cm2/dyn for an average MCHC of 32.12 .+-. 1.51 g%. The relationship between the MCHC and compressibility was investigated by suspending erythrocytes in saline of different NaCl concentrations. A r = 0.932 was obtained from linear regression analysis.

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