Synergisms and Antagonisms of Estrogens and Progesterone in a Mouse Uterine Bio-assay
- 1 August 1966
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 79 (2) , 420-423
- https://doi.org/10.1210/endo-79-2-420
Abstract
Bio-assay by the Hooker-Forbes method for progestin activity of mixtures of progesterone with estrone and with 17[beta]-estradiol revealed complete inhibition, partial inhibition, no interference, or synergism, depending on the proportions of the mixtures. Bio-assay of progesterone:estriol mixtures indicated partial or complete antagonism. These mechanisms may exercise significant control of the action of progesterone.This publication has 0 references indexed in Scilit: