Substitutions at Phe61 in the β3-β4 Hairpin of HIV-1 Reverse Transcriptase Reveal a Role for the Fingers Subdomain in Strand Displacement DNA Synthesis
- 17 December 2002
- journal article
- Published by Elsevier in Journal of Molecular Biology
- Vol. 325 (3) , 443-459
- https://doi.org/10.1016/s0022-2836(02)01225-1
Abstract
No abstract availableKeywords
This publication has 45 references indexed in Scilit:
- Substitutions of Phe61 Located in the Vicinity of Template 5′-Overhang Influence Polymerase Fidelity and Nucleoside Analog Sensitivity of HIV-1 Reverse TranscriptaseJournal of Biological Chemistry, 2002
- Cross-Linking of the Fingers Subdomain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase to Template-PrimerJournal of Virology, 2001
- Structural alterations in the DNA ahead of the primer terminus during displacement synthesis by reverse transcriptasesJournal of Molecular Biology, 2001
- Compression of the DNA Minor Groove is Responsible for Termination of DNA Synthesis by HIV-1 Reverse TranscriptaseJournal of Molecular Biology, 1999
- Properties of strand displacement synthesis by moloney murine leukemia virus reverse transcriptase: mechanistic implicationsJournal of Molecular Biology, 1998
- Characterization of RNA Strand Displacement Synthesis by Moloney Murine Leukemia Virus Reverse TranscriptaseJournal of Biological Chemistry, 1998
- Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNANature, 1997
- Reduced Frameshift Fidelity and Processivity of HIV-1 Reverse Transcriptase Mutants Containing Alanine Substitutions in Helix H of the Thumb SubdomainPublished by Elsevier ,1995
- Locations of Anti-AIDS Drug Binding Sites and Resistance Mutations in the Three-dimensional Structure of HIV-1 Reverse TranscriptaseJournal of Molecular Biology, 1994
- HIV-1 Reverse Transcription A Termination Step at the Center of the GenomeJournal of Molecular Biology, 1994