Effect of four i.v. induction agents on T-lymphocyte proliferations to PHA in vitro
Open Access
- 1 September 1994
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 73 (3) , 315-317
- https://doi.org/10.1093/bja/73.3.315
Abstract
Anaesthetic agents are believed to have an adverse effect on human immunity. We have studied the effects of four i.v. induction agents, thiopentone, methohexitone, etomidate and propofol, on T-lymphocyte proliferations to phytohaemagglutinin in vitro. We found that at plasma concentrations similar to those obtained after induction doses, all drugs, with the exception of propofol, caused depression of T-lymphocyte function.Keywords
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