Studies on isocyanides and related compounds: synthesis of benzo[c]thiophenes by way of acid-induced three-component reactions

Abstract
The ‘diimino thioanhydrides’ of cyclohex-l-ene-1,2-dicarboxylic acid have been synthesized in a very simple manner by allowing 2-(arylaminothiocarbonyl)cyclohexanones 1 and isocyanides 3 to react in an acidic medium. A mechanism for this three-component reaction, based on isocyanide chemistry, is proposed.

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