Synthese von 1-Aminoalkanphosphonsäuren via Benzhydrylschiffbasen / Synthesis of 1-Aminoalkane Phosphonic Acids via Benzhydrylic Schiff Bases

Abstract
A simple synthesis of 1-aminoalkanephosphonic acids is described. The addition of diethylphosphite to alkylidene-and arylidenebenzhydrylamines yields the N-benzhydryl-1-aminoalkanphosphonic acid esters. The title compounds are formed by treatment of the N-blocked esters with hydrobromic acid. The starting amine can be recycled from the hydrylbromide.

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