Chemistry of Amino Acids. IV. Decarboxylation of 1, 2, 3, 4-Tetrahydroisoquinoline-3-carboxylic Acid and Its Derivatives

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Abstract
Decarboxylation of 1, 2, 3, 4-tetrahydroisoquinoline-3-carboxylic acid derivatives, I, II, III, IV and IV hydrochloride, in acetophenone and benzaldehyde as solvents, was examined. It was found that in the case of IV hydrochloride, 4-substituted isoquinoline derivatives were formed in moderate yield according to the solvent used.

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