Abstract
The first and second years' observations on the results of the treatment of neurosyphilis by means of malaria were given in two previous reports.1I now report the status of the original 100 patients treated by this method, and also call attention to other features noted in the observation of 113 patients treated subsequently. The treatment by malaria in the Mayo Clinic has been used particularly in the resistant parenchymatous forms of neurosyphilis, including the persistent and incapacitating gastric crises, "lightning" pains in the legs, and the optic atrophy of tabes dorsalis. Enthusiasm has not as yet carried us to the point of applying the treatment to patients with the acute signs of syphilis or the latent form of the disease. Neither have the proved standard methods of treating neurosyphilis by the use of arsphenamine, tryparsamide, intraspinal medication, mercury or bismuth, and sodium iodide intravenously been discarded because, according

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