Synthesis of N-nitrosamino aldehydes, metabolic intermediates possibly involved in the induction of tumors in rats by N-butyl-N-(.OMEGA.-hydroxyalkyl)nitrosamines.

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Abstract
Three N-nitrosamino aldehydes, N-butyl-N-(ω-formylalkyl) nitrosamines, which are necessary metabolic intermediates situated between N-butyl-N-(ω-hydroxyalkyl)-nitrosamines and N-butyl-N-(ω-carboxyalkyl) nitrosamines were synthesized for the purpose of investigating their mutagenic effects.

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