Increased synaptosomal dopamine content and brain concentration of paraquat produced by selective dithiocarbamates
Open Access
- 23 April 2003
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 85 (4) , 1075-1086
- https://doi.org/10.1046/j.1471-4159.2003.01773.x
Abstract
Exposure to pesticides may be a risk factor for Parkinson's disease based on epidemiologic data in humans, animal models and in vitro studies. Different dithiocarbamate pesticides potentiate the toxi...Keywords
This publication has 57 references indexed in Scilit:
- Effects of probenecid on striatal dopamine depletion in acute and long-term 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated micePublished by Elsevier ,2002
- The Impact of Efflux Transporters in the Brain on the Development of Drugs for CNS DisordersClinical Pharmacokinetics, 2002
- ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humansJournal of Molecular Biology, 1999
- Acetaldehyde directly enhances MPP+ neurotoxicity and delays its elimination from the striatumBrain Research, 1989
- MPTP treatment combined with ethanol or acetaldehyde selectively destroys dopaminergic neurons in mouse substantia nigraBrain Research, 1989
- Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomesBiochemical and Biophysical Research Communications, 1985
- IV. Differences in the metabolism of MPTP in the rodent and primate parallel differences in sensitivity to its neurotoxic effectsLife Sciences, 1985
- Interaction between dopamine influx and efflux in rat striatal synaptosomesLife Sciences, 1982
- Uptake and efflux of 14C-paraquat by rat lung slices: The effect of imipramine and other drugsToxicology and Applied Pharmacology, 1979
- In vivo oxidation of reduced nicotinamide-adenine dinucleotide phosphate by paraquat and diquat in rat lungChemico-Biological Interactions, 1977